God

Original Series
In the original series God was not featured very much. However, he was who Mathias blamed for his wife's death. After Mathias' wife died, he was supposedly bedridden with grief. However, the truth was that he harbored a great resentment towards God. He believed that since he risked his life in the name of God he did not deserve to have his wife, Elizabetha, taken from him.

As a result, he engineered an elaborate scheme to turn into a powerful vampire, claiming that if God's decree was a mortal life, then he shall defy it. This was the catalyst for Mathias becoming the vampire the world would later know as Dracula.

In addition, the art of alchemy was described as the principled study of God's creation of this world.

Lords of Shadow
In Lords of Shadow God was more prominent. The order to which Gabriel Belmont belonged was essentially an order that protected people for God. In addition, the main antagonist Satan's true goal was an attack against God. And though God never appears, he is somewhat like an unseen protagonist.

Throughout the game Gabriel begins to question his faith. But in the end he sees the truth in God's message in comparison to Satan's goals. He tells Satan that God loves them both and that they only need to ask and they will be forgiven. He rebukes Satan's claim to rule as equals to or above God and for prefering to rule with power and might, rather than offer love and forgiveness. In the end Gabriel defeats Satan and asks for forgiveness from God.

But Gabriel was apparently denied foregiveness, and ultimately cursed God. It is one of the things that lead to his corruption into becoming the new Prince of Darkness, Dracula.