Rue

Rue is an item in Castlevania: Order of Ecclesia. One can be found at plain sight on a high ledge at Misty Forest Road. They can also be found as random drops from common wooden item boxes in Tymeo Mountains, Tristis Pass and Argila Swamp.

One must be given to Abram, along with a Chamomile, in order to complete the "Unusual Medicine Components" quest, which adds Anti-Venoms and Uncurse Potions to Jacob's shop.