In 1830, she successfully resurrected Count Dracula, although he was not at his full power. To restore his evil might, Camilla planned to sacrifice the vampire hunter Morris Baldwin, father of Hugh Baldwin and mentor to Nathan Graves, during a lunar eclipse of the full moon. As Graves began making headway in an effort to rescue his master, Camilla sent the Necromancer to delay him. Ultimately, she brainwashed Hugh to do her evil bidding and challenged Graves to a battle in the Underground Waterway.
She later meets Nathan, whom she tries to convince to stop fighting, claiming that darkness was the true nature of the human soul, therefore meaning he shouldn't fight Dracula, but Nathan ignored her point of view. Although she perished at the hero's hand, Camilla relished the fact that the rite to restore the Count was nearly complete.
In Circle of the Moon, Camilla plays a much larger role as the main antagonist in this game than in previous installments. Camilla is the mastermind behind all events taking place in this story, from the resurrection of Dracula, the summoning of the Necromancer, the abduction of Morris Baldwin, the conversion of Hugh, and the deployment of all creatures to allow her master to regain all his power.
When confronted, Camilla transforms into a winged demon atop a flying giant skull. While a different look for her, she still resembles her previous appearances. She attacks with an array of different forms of dark energy: homing fumes, a barrage of blade-shaped blasts, and a constant stream of energy emitted from the skull's mouth. After the battle, she will revert to her normal form and tell Nathan that he is too late and there is no way to stop Dracula, then she screams as she dies and her body disintegrates into dust.
- Camilla is an alternate spelling of Carmilla. The first time the name "Camilla" was used, was in Castlevania II: Simon's Quest, and later in Rondo of Blood.
- The events taking place in Circle of the Moon are considered to be non-canon in the series timeline, so this version of Carmilla can be considered to be an unique character.
- Defeating Camilla triggers the following three enemies to appear in diverse areas of the castle:
|Castlevania: Circle of the Moon|
Camilla • Dracula
Sealed Room • Catacomb • Abyss Stairway • Audience Room • Triumph Hallway • Outer Wall • Machine Tower • Eternal Corridor • Chapel Tower • Underground Gallery • Underground Warehouse • Underground Waterway • Observation Tower • Ceremonial Room • Battle Arena